Changing the course of inherited disease, together.

Rewriting the odds

The search for new medicines is getting slower, more expensive, and less successful. For families living with inherited disease, "eventually" isn't fast enough.

By grounding our research in human genetics, we focus on the biological drivers most likely to lead to better, safer treatments.

90%

of drug candidates fail in clinical development

>2X

higher success rate for candidates with genetic evidence

The Newfoundland and Labrador advantage

Local insights

Newfoundland and Labrador’s founder population has a higher frequency of certain genetic variants, some of which have already been linked to conditions like cancer and heart disease. Building on this important work, we are expanding the search for the genetic causes of some of the most medically challenging diseases.

Learn about our approach

Global impact

By uncovering novel links between genes and disease, we enable the identification of promising targets for drug development and biomarkers for precision medicines. With a focus on global unmet medical need, we believe that discoveries made here can transform how disease is treated for patients everywhere.

Our Studies

Study of Genetic Cause of Inherited Diseases in Newfoundland and Labrador

Conducted in partnership with NL Health Services, this study investigates a range of inherited diseases that reflect our province’s unique genetic landscape and deep family health histories. Enrollment is now open to eligible Newfoundlanders and Labradorians.

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Study of Familial Ovarian Cancer

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Study of Familial Multiple Sclerosis

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Study of Familial Idiopathic Pulmonary Fibrosis

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NL Genome Project

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For patients and medical professionals

Progress starts with those closest to disease. Whether you are living with a condition or treating one, your participation is what moves research forward.

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